Giulia Menichetti (Moderator), Jan Baumbach, Joseph Loscalzo, and Manlio De Domenico

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Network Medicine is an evolving discipline that underscores the significance of comprehensive molecular interactions in disease prevention and treatment. It leverages the human interactome—a vast subcellular map of all known physical and regulatory interactions between human proteins and RNAs—to enhance our understanding of disease mechanisms, drug discovery, and repurposing. The structure of this interactome is crucial for efficiently propagating biological signals and ensuring resilience against random failures, exhibiting the universal scale-free topology’s typical error/attack tolerance and cascading failure emergence.

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Network Medicine primarily focuses on quantifying communication efficiency between different regions of the interactome and assessing their deviations from expectation. This panel will feature discussions with Prof. Loscalzo, Prof. Baumbach, and Prof. De Domenico on emerging trends in Network Medicine, including systems pharmacology and the integration of diverse biological datatypes with AI methodologies and multilayer networks.

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